No. Selected Publications:
1 Saifer MG, Williams LD, Sobczyk MA, Michaels SJ, Sherman MS (2014) Selectivity of binding of PEGs and PEG-like oligomers to anti-PEG antibodies induced by methoxyPEG-proteins. Mol Immunol 57(2014):236-246.
2 Sherman MR, Saifer MG, Williams LD, Michaels SJ, Sobczyk MA (2012) Next-generation PEGylation enables reduced immunoreactivity of PEG-protein conjugates. Drug Dev. & Del. 12(5):36-42.
3 Sherman MR, Williams LD, Sobczyk MA, Michaels SJ, Saifer MG (2012) Role of the methoxy group in immune responses to mPEG-protein conjugates. Bioconjug Chem 23:485-499. Supporting Information
4 Sherman M, Saifer MG, Perez-Ruiz F, (2008) PEG-uricase in the management of treatment-resistant gout and hyperuricemia. Adv Drug Deliv Rev 60:59-68.
5 Kelly SJ, Delnomdedieu M, Oliverio MI, Williams LD, Saifer MGP, Sherman MR, Coffman TM, Johnson GA, Hershfield MS (2001) Diabetes insipidus in uricase-deficient mice: A model for evaluating therapy with poly(ethylene glycol)-uricase.
J Am Soc Nephrol
6 Sherman MR, Williams LD, Saifer MGP, French JA, Kwak LW, Oppenheim JJ (1997) Conjugation of high molecular weight poly(ethylene glycol) to cytokines: Granulocyte-macrophage colony-stimulating factors as model substrates. in:
Poly(ethylene glycol) Chemistry and Biological Applications. ACS Symposium Series 680
, Harris JM, Zalipsky S, eds., American Chemical Society, Washington, DC, pp 155-169.
7 Saifer MGP, Williams LD, Sherman MR, French JA, Kwak LW, Oppenheim JJ (1997) Improved conjugation of cytokines using high molecular weight poly(ethylene glycol): PEG-GM-CSF as a prototype. Polymer Preprints 38:576-577.
8 Smith RA, Balis FM, Ott KH, Elsberry DD, Sherman MR, Saifer MP, (1995) Pharmacokinetics and tolerability of ventricularly administered superoxide dismutase in monkeys and preliminary clinical observations in familial ALS. J Neurol Sci 129 (Suppl):13-18.
9 Saifer MGP, Somack R, Williams LD (1994) Plasma clearance and immunologic properties of long-acting superoxide dismutase prepared using 35,000 to 120,000 dalton poly-ethylene glycol (PEG).Adv Exp Med Biol 366:377-387.
10 Saifer MGP, Somack R, Williams LD (1994) Plasma clearance and immunologic properties of long-acting superoxide dismutase prepared using 35,000-120,000 dalton poly-ethylene glycol (PEG). in: Frontiers of Reactive Oxygen Species in Biology and Medicine, Asada K, Yoshikawa T, eds., Elsevier, Amsterdam, pp 423-424.
11 Somack R, Saifer MGP, Williams LD (1991) Preparation of long-acting superoxide dismutase using high molecular weight polyethylene glycol (41,000-72,000 daltons). Free Radic Res Commun 12-13:553-562.
12 Maayani S, Sherman MR (1990) Adenylate cyclase-linked 5-hydroxytryptamine receptors in the brain. in: Serotonin: From Cell Biology to Pharmacology and Therapeutics, Paoletti R, Vanhoutte PM, Brunello N, Maggi FM, eds., Kluwer Academic Publishers, Dordrecht, The Netherlands, pp 39-51.
13 Saifer MGP, Williams LD, Dang PH-C, Somack R, Sloan C, Miranda QR (1986) Orgotein, the drug version of bovine copper, zinc superoxide dismutase: III. Properties of injectable superoxide dismutase. in: Superoxide and Superoxide Dismutase in Chemistry, Biology and Medicine, Rotilio G, ed., Elsevier, Amsterdam, pp 493-496.
14 Sherman MR, Tuazon FB, Stevens YW, Carlino JA, Niu E-M (1986) "Defective" receptors in steroid-resistant conditions may be proteolytic artifacts. Adv Exp Med Biol 196:23-51.
15 Gorsline J, Bradlow HL, Sherman MR (1985) Triamcinolone acetonide 21-oic acid methyl ester: A potent local antiinflammatory steroid without detectable systemic effects. Endocrinology 116:263-273.
16 Sherman MR, Stevens J (1984) Structure of mammalian steroid receptors: Evolving concepts and methodological developments. Annu Rev Physiol 46:83-105.
17 Sherman MR, Stevens Y-W, Tuazon FB (1984) Multiple forms and fragments of cytosolic glucocorticoid receptors from human leukemic cells and normal lymphocytes. Cancer Res 44:3783-3796.
18 Sherman MR, Tuazon FB, Stevens Y-W, Niu E-M (1983) Oligomeric steroid receptor forms and the products of their dissociation and proteolysis. in: Steroid Hormone Receptors: Structure and Function, Proceedings of the 57th Nobel Symposium, Karlskoga, Sweden, 1983, Eriksson H, Gustafsson J-Å, eds., Elsevier, Amsterdam, pp 3-24.
19 Sherman MR, Moran MC, Tuazon FB, Stevens Y-W (1983) Structure, dissociation, and proteolysis of mammalian steroid receptors. Multiplicity of glucocorticoid receptor forms and proteolytic enzymes in rat liver and kidney cytosols. J Biol Chem 8:10366-10377.
20 Miller LK, Tuazon FB, Niu E-M, Sherman MR (1981) Human breast tumor estrogen receptor: Effects of molybdate and electrophoretic analyses. Endocrinology 108:1369-1378.
21 Niu E-M, Neal RM, Pierce VK, Sherman MR (1981)Structural similarity of molybdate-stabilized steroidreceptors in human breast tumors, uteri and leukocytes.
J Steroid Biochem
22 Lee HJ, Bradlow HL, Moran MC, Sherman MR (1981) Binding of glucocorticoid 21-oic acids and esters to molybdate-stabilized hepatic receptors. J Steroid Biochem 14:1325-1335.
23 Sherman MR, Tuazon FB, Sömjen GJ (1981) Stabilization and cleavage of steroid receptors: Effects of leupeptin and molybdate on rat and kidney glucocorticoid receptors. Prog Clin Biol Res 74:321-337.
24 Sherman MR, Tuazon FB, Miller LK (1980) Estrogen receptor cleavage and plasminogen activation by enzymes in human breast tumor cytosol. Endocrinology 106:1715-1727.
25 Huber W, Menander-Huber KB, Saifer MGP, Williams LD (1980) Bioavailability of superoxide dismutase: Implications for the anti-inflammatory action mechanism of orgotein. Agents Actions (Supplement) 7:185-195.
26 Williams LD, Saifer MG, Dang PH-C, Huber W (1980) Development of an arthus-like model of induced inflammation and its use in the antiinflammatory characterization of orgotein (bovine Cu,Zn superoxide dismutase). in: Inflammation: Mechanism and Treatment, Willoughby DA, Giroud JP, eds., MTP Press, Lancaster UK, pp 149-156.
27 Huber W, Saifer MGP, Williams LD (1980) Superoxide dismutase pharmacology and orgotein efficacy: New perspectives. in: Developments in Biochemistry, Vol. 11B, Bannister WH, Bannister JV, eds., Elsevier, Amsterdam, pp 395-407.
28 Sherman MR, Barzilai D, Pine PR, Tuazon FB (1979) Glucocorticoid receptor cleavage by leupeptin-sensitive enzymes in rat kidney cytosol. Adv Exp Med Biol 117:357-375.
29 Sherman MR (1979) Allosteric and competitive steroid-receptor interactions. Monogr Endocrinol 12:123-133.
30 Bullock LP, Bardin CW, Sherman MR (1978)Androgenic, antiandrogenic, and synandrogenic actions of progestins: Role of steric and allosteric interactions with androgen receptors. Endocrinology 103:1768-1782.
31 Sherman MR, Pickering LA, Rollwagen FM, Miller LK (1978) Mero-receptors: Proteolytic fragments of receptors containing the steroid-binding site. Fed Proc 37:167-173.
32 Huber W, Saifer MGP (1977) Orgotein, the drug version of bovine Cu,Zn superoxide dismutase: I. A summary account of safety and pharmacology in laboratory animals. in: Superoxide and Superoxide Dismutases, Michelson AM, McCord JM, Fridovich I, eds., Academic Press, London, pp 517-536.
33 Huber W, Menander-Huber KB, Saifer MGP, Dang PH-C (1977) Studies on the clinical and laboratory pharmacology of drug formulations of bovine Cu-Zn superoxide dismutases (orgotein). in: Perspectives in Inflammation. Future Trends and Developments, Willoughby DA, Giroud J P, Velo GP eds., University Park Press, Baltimore, pp 527-540.
34 Sherman MR, Diaz SC (1977) Mero-receptor formation from a larger subcomponent of the oviduct progesterone receptor. Ann NY Acad Sci 286:81-86.
35 Friedman M, Williams LD (1977) A mathematical analysis of kinetics of consecutive, competitive reactions of protein amino groups. Adv Exp Med Biol 86B:299-319.
36 Sherman MR, Tuazon FB, Diaz SC, Miller LK (1976) Multiple forms of oviduct progesterone receptors analyzed by ion exchange filtration and gel electrophoresis. Biochemistry 15:980-989.
37 Sherman MR, Miller LK (1976) Fractionation of diverse steroid-binding proteins: Basic and clinical application. Curr Top Mol Endocrinol 4:51-67.
38 Sherman MR (1975) Physical-chemical analysis of steroid hormone receptors. Methods Enzymol 36:211-234.
39 Toft DO, Sherman MR (1975) Receptor identification by density gradient centrifugation. Methods Enzymol 36:156-166.
40 Miller LK, Diaz, Sherman MR (1975) Steroid-receptor quantitation and characterization by electrophoresis in highly cross-linked polyacrylamide gels. Biochemistry 14:4433-4443
41 Sherman MR, Atienza S-BP, Shansky JR, Hoffman LM (1974) Progesterone receptors of chick oviduct. Steroid-binding “subunit” formed with divalent cations. J Biol Chem 249:5351-5363
42 Friedman M, Williams LD, Masri MS (1974) Reductive alkylation of proteins with aromatic aldehydes and sodium cyanoborohydride. Int J Pept Protein Res 6:183-185.
43 Friedman M, Williams LD (1973) The reaction of ninhydrin with keratin proteins.
Anal Biochem 54:333-345.
44 O'Malley BW, Toft DO, Sherman MR (1971) Progesterone-binding components of chick oviduct. II. Nuclear components. J Biol Chem 246:1117-1122.
45 Sherman MR, Corvol PG, O’Malley BW (1970) Progesterone-binding components of chick oviduct. I. Preliminary characterization of cytoplasmic components. J Biol Chem 245 6085-6096.
46 O'Malley BW, Sherman MR, Toft DO (1970) Progesterone “receptors” in the cytoplasm and nucleus of chick oviduct target tissue. Proc Natl Acad Sci USA 67:501-508.
47 Kluger R, Covitz F, Dennis E, Williams LD, Westheimer F (1969) pH-Product and pH-rate profiles in the hydrolysis of methyl ethylene phosphate. Rate-limiting pseudorotation. J Am Chem Soc 91:6066-6072.
48 Piez KA, Sherman MR (1970) Characterization of the product formed by renaturation of alpha 1-CB2, a small peptide from collagen. Biochemistry 9:4129-4133.
49 Piez KA, Sherman MR (1970) Equilibrium and kinetics studies of the helix-coil transition in alpha 1-CB2, a small peptide from collagen. Biochemistry 9:4134-4140.
50 Rubin (Sherman) MM, Piez KA, Katchalsky A (1969) Equilibrium mechanochemistry of collagen fibers. Biochemistry 8:3628-3637.
51 Changeux J-P, Rubin (Sherman) MM (1968) Allosteric interactions in aspartate transcarbamylase. III. Interpretation of experimental data in terms of the model of Monod, Wyman and Changeux. Biochemistry 7:553-561.
52 Rubin (Sherman) MM, Changeux J-P (1966) On the nature of allosteric transitions: Implications of non-exclusive ligand binding. J Mol Biol 21:265-274.
53 Rubin (Sherman) MM, Katchalsky A (1966) Mathematics of band centrifugation: Concentration-independent sedimentation and diffusion in shallow density gradients. Biopolymers 4:579-593.